Setting up a set of equations

Im having some trouble wiht this problem, i was wondering if any one could help?

there are three equations

u = [0.25*S]/[S+0.005]

dS/dt = -0.42uX

dX/dt = uX

with the initial conditions at to, xo = 2, s0 = 63.6
I set up the Mfile for u, but i have no idea how to set up the differentials so that i get a plot of change in S and X onver time.

Can anyone please help?
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